Early Development Group Lead (VP) – Oncology
Locations:
United States – Washington, Bothell
United States – California, La Jolla
United States – Massachusetts, Cambridge
United States – Connecticut, Groton
United States – New York, New York City
Employment Type: Full-Time
Posted: Yesterday
Job Requisition ID: 4950055
Role Summary:
Pfizer is seeking an experienced Early Development Group Lead (VP) to provide strategic oversight across multiple early-stage oncology programs. This role manages Global Development Product Leads, directs clinical trial planning and execution, and serves as a scientific and medical resource for Pfizer. Responsibilities include supporting early-stage development strategy, business development clinical diligence, and process improvements across the oncology portfolio.
Key Responsibilities:
Strategic Leadership
Lead and provide strategic oversight of a substantial portion of the early pipeline within Oncology Early Stage Development.
Manage multiple Global Development Product Leads to ensure cross-functional collaboration, scientific excellence, and efficient decision-making.
Serve as a scientific/medical resource for Pfizer, supporting business development clinical diligence and internal process improvements.
Act as interim coverage for Global Development Product Leads as needed, providing leadership to early-stage product teams and clinical study teams.
Clinical Development & Program Management
Guide cross-functional strategic development of early-stage programs from pre-IND to Phase 1 proof-of-concept.
Review and provide input on IND applications, clinical protocols, investigator brochures, and clinical study reports.
Collaborate with translational sciences to interpret preclinical and nonclinical data and inform clinical strategy.
Evaluate safety, pharmacology, biomarker, and efficacy data from ongoing and completed studies.
Provide clinical and medical guidance for study design, interpretation of preclinical/clinical programs, and regulatory interactions.
Scientific Communication & Content Development
Review manuscripts, abstracts, and presentations for scientific meetings and advisory boards.
Conduct literature reviews and prepare summaries to support clinical development programs.
Serve as a medical resource for the design and interpretation of clinical and preclinical programs.
Stakeholder & External Collaboration
Collaborate with internal and external partners including health authorities, clinical investigators, scientists, and key opinion leaders (KOLs).
Drive cross-functional initiatives contributing to process improvements, training, and other development workstreams.
Ensure appropriate medical oversight and interpretation of clinical studies while maintaining patient safety and data integrity.
Team Leadership & Talent Development
Attract, hire, motivate, and develop top talent within early-stage oncology development teams.
Mentor and guide Global Development Product Leads and cross-functional team members to achieve strategic and operational objectives.
Required Qualifications
MD or MD/PhD with clinical oncology experience; Board certification in oncology or hematology preferred.
Minimum 10+ years of industry experience in oncology drug development, including early-stage clinical trial design and execution.
Proven leadership and executive presence with a strong track record of mentoring and managing cross-functional teams.
Deep understanding of drug development from preclinical through commercial stages.
Passion for oncology research and improving patient outcomes.
Excellent communication, collaboration, and interpersonal skills with global teams.
Preferred Qualifications
Experience in strategic decision-making, clinical development oversight, and regulatory interactions.
Proven analytical skills and ability to work with large datasets.
Global mindset and experience working with diverse teams across multiple geographies.
Strong publication record, including manuscripts, abstracts, or presentations.
Ability to drive process improvements and foster a culture of innovation.
Experience Required
10+ years of leadership experience in oncology drug development, managing early-stage clinical programs.
Hands-on experience with pre-IND to Phase 1 proof-of-concept studies, cross-functional team leadership, and clinical strategy development.
Demonstrated success in mentoring teams, guiding decision-making, and influencing scientific and operational outcomes.
Work Arrangement & Benefits
Full-time role with potential for global travel.
Annual base salary: $330,200 – $514,400, with eligibility for Pfizer’s Global Performance Plan (30% bonus target) and long-term incentive programs.
Comprehensive benefits including 401(k) with matching contributions, paid vacation, parental leave, and health coverage.
Relocation assistance may be available based on business needs and eligibility.
Why Pfizer
Pfizer is committed to diversity, equity, and inclusion and offers a collaborative environment where scientific leadership drives innovation in oncology research. Join us to advance early-stage clinical development and make a meaningful impact on patients’ lives.
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