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    Principal Scientist – Lcms & Large Molecule Research

    Icon Plc
    ICON PLC
    5+ years
    Not Disclosed
    New York, Whitesboro, United States
    1 May 7, 2026
    Job Description
    Job Type: Full Time Education: Minimum: Master’s degree (MA/MS) in Medicine, Neurology, Psychology, or related field. Preferred: MD, DO, or PhD. Skills: Clinical Trials, Functional Teams, Literature Review, Management Skills, Medical Information, Medical Records, Medical Strategy, Pharmacovigilance, Regulatory Compliance, Risk Management, Safety Scien, Coaching Skills, Data Science, Environment, Experiments Design, Health And Safety (Ehs), Laboratory Equipment, Manufacturing Process, Materials Science, Process Simulation, Sop (Standard Operating Pro, Collaboration, Communication Skills, gmp, GMP Guidelines, Operational Excellence, Problem Solving Skills, Quality Agreements, Quality Compliance, Quality Management, Quality Standards, Regulatory Requ, Communication Skills, Continual Improvement Process, Master Data, Material Requirements Planning (Mrp), Materials Management, People Management, Production Planning, Supplier Relationship Management (Srm), Supply-Chain Man, CPC Certified, Data Analysis, Document Management, Life Science, Regulatory Compliance, Waterfall Model, Environment, Experiments Design, Health And Safety (Ehs), Laboratory Equipment, Manufacturing Process, Materials Science, Process Simulation, Sop (Standard Operating Procedure), Technical Writing, Wat, GCP guidelines, gmp knowledge, HSE Knowledge , Logistics and Transportation Management, Master Data, Operational Excellence, Sap Erp, supply chain management, Supply Planning, Warehouse Management, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, mRS and EQ-5D-5L., Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

    Principal Scientist – LCMS & Large Molecule Research

    Company: ICON plc
    Job Title: Principal Scientist
    Location: Whitesboro, New York, United States
    Work Mode: On-Site
    Job Type: Full-Time
    Industry: Bioanalytical Research / Pharmaceutical / Clinical Research / Mass Spectrometry
    Experience Required: 5+ Years
    Salary Range: $75,480 – $94,350 per year

    Job Overview

    ICON plc is seeking an experienced Principal Scientist with strong expertise in LCMS, LCMSMS, Hybrid Mass Spectrometry, and Large Molecule Analysis to join its scientific research team in Whitesboro, New York.

    This role focuses on advanced bioanalytical and mass spectrometry-based research activities supporting clinical and pharmaceutical development programs. The selected candidate will contribute to scientific innovation, analytical workflow optimization, client collaboration, and study data interpretation while working in a highly regulated laboratory environment.

    The position is ideal for professionals with deep experience in large molecule bioanalysis, protein sequencing, LC-MS/MS instrumentation, and analytical sciences.

    Key Responsibilities

    Scientific Research & Bioanalytical Analysis

    • Perform advanced scientific and analytical activities within the LCMS laboratory environment.
    • Support large molecule and hybrid mass spectrometry research programs.
    • Analyze and interpret complex bioanalytical and mass spectrometry data.
    • Summarize scientific study findings and support reporting activities.

    LCMS & Mass Spectrometry Operations

    • Work extensively with:
      • LCMS systems
      • LCMSMS instrumentation
      • Hybrid mass spectrometry platforms
      • Protein sequencing technologies
    • Utilize analytical software tools such as:
      • Skyline
      • In-silico sequencing software
      • Other protein analysis platforms
    • Support workflow optimization and scientific process improvements.

    Project Coordination & Client Communication

    • Collaborate with project managers to:
      • Prepare project timelines
      • Track deliverables
      • Ensure timely completion of analytical tasks
    • Provide study updates and scientific insights to clients and internal stakeholders.
    • Participate in team meetings, scientific discussions, and project reviews.

    Scientific Publications & Innovation

    • Prepare scientific publications and research documentation.
    • Attend:
      • Scientific seminars
      • Workshops
      • Industry conferences
    • Stay updated with emerging trends in:
      • Mass spectrometry
      • Protein analysis
      • Bioanalytical sciences
      • Large molecule research

    Operational Excellence & Process Improvement

    • Support continuous improvement initiatives across laboratory operations.
    • Identify workflow challenges and recommend scientific solutions.
    • Contribute to optimization of analytical and operational processes.

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