Scientist – Purification Process Development
Location: Pune, Maharashtra, India | Employee Type: Permanent | Department: Purification Process Development
Company Overview:
Join a leading biopharmaceutical organization dedicated to developing recombinant proteins, antibodies, and therapeutic biologics. Our team drives innovation in process development, scale-up, and technology transfer to deliver high-quality biotherapeutics globally.
Role Overview:
We are seeking a Scientist to support downstream process development for mammalian or microbial expressed proteins. The candidate will execute experiments, analyze data, support cross-functional projects, and maintain lab operations under the guidance of the manager. This role requires strong technical expertise in protein purification processes, troubleshooting, and documentation.
Key Responsibilities:
Plan and execute downstream process activities for mammalian/microbial products or recombinant proteins.
Capture, compile, and interpret experimental data, coordinating with the reporting manager.
Prepare, review, and present development reports, BPRs, SOPs, EOPs, and IOPs.
Participate in internal and external meetings representing the department.
Prioritize activities, provide feasibility insights for prospective projects, and troubleshoot technical issues in manufacturing.
Manage laboratory operations, including cleanliness, equipment maintenance, and compliance with EHS standards.
Facilitate communication with internal teams and external vendors/clients for technical queries.
Technical Skills Required:
Expertise in protein purification and process development: Chromatography, Depth Filtration, Centrifugation, UFDF, Sterile Filtration.
Hands-on experience in process monitoring, QbD, and DoE-based process development.
Data analytics proficiency and experience with scale-up/down, technology transfer, and virus clearance (VCS) studies.
Operation, troubleshooting, and routine maintenance of lab purification equipment (Chromatography systems, UFDF, pH/conductivity meters).
Familiarity with protein analytical techniques (protein assays, gel electrophoresis, HPLC) is an advantage.
Ability to work independently, lead small teams, and document experimental results effectively.
Qualifications & Experience:
MSc, M.Tech, M.Pharm, or equivalent Master’s degree in Biological Sciences from a recognized university.
8–11 years of relevant experience in downstream process development for therapeutic proteins.
Soft Skills:
Strong communication and teamwork abilities.
Enthusiasm, motivation, and dedication to achieving high-quality results.
Why Join Us:
This role provides exposure to advanced bioprocessing techniques, cross-functional collaboration, and hands-on experience in developing and scaling therapeutic biologics.
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