Job Summary:
Novo Nordisk is seeking a talented Scientist II – Oligonucleotide Medicinal Chemistry for its cutting-edge Global Nucleic Acid Therapies division in Lexington, USA. This role offers a unique opportunity to contribute to novel RNA and gene therapies, working on oligonucleotide synthesis and drug delivery platform innovations. Collaborate with a multidisciplinary team in a dynamic, fast-paced biotech environment focused on revolutionizing genetic medicines.
Key Responsibilities:
Design and execute multi-step organic synthesis for novel target compounds.
Propose new target molecules by reviewing scientific literature and patents.
Independently develop research projects supporting siRNA delivery platforms.
Operate and maintain HPLC and LCMS for compound analysis and purification.
Lead internal and external chemists' research efforts as needed.
Present research outcomes in departmental and cross-functional meetings.
Plan in vitro and in vivo experiments collaboratively to optimize drug delivery.
Aid in drafting intellectual property, publications, and strategic project plans.
Contribute to scientific presentations and publications alongside peers.
Required Skills & Qualifications:
BS/BA with 8+ years, MS with 6+ years, or PhD with 2+ years of relevant experience.
Expertise in modern organic synthesis, reaction mechanisms, and complex molecule development.
Strong background in analytical and purification techniques.
Excellent data analysis and project planning abilities.
Self-driven, proactive, and adaptable in a fast-paced environment.
Superior written and verbal communication skills.
Preferred: experience in oligonucleotide chemistry, heterocyclic synthesis, bio-conjugation, or medicinal chemistry.
Perks & Benefits:
Competitive base salary: $96,670 – $178,840 per year.
Annual performance-based bonus.
Long-term incentive plans.
Comprehensive health coverage: medical, dental, vision.
Life and disability insurance.
401(k) retirement savings plan with company contribution.
Flexible spending accounts and tuition reimbursement.
Paid parental leave, flexible vacation, and sick leave policies.
Additional voluntary benefits: legal services, critical illness coverage, identity theft protection, pet and home insurance.
Company Description:
Novo Nordisk is a global leader in pharmaceutical innovation, driving transformative therapies in diabetes care, rare diseases, and RNA-based medicines. Their Lexington hub specializes in nucleic acid therapies, fostering breakthrough drug discovery in a collaborative, high-tech environment.
Work Mode:
On-site – Lexington, Massachusetts, USA
Call-to-Action:
Ready to shape the future of genetic medicine? Apply now to join Novo Nordisk’s pioneering nucleic acid therapeutics team in Lexington.
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