Job Title
Materials Science Crystallization Advisor-SMDD
Location
Indianapolis, Indiana, United States
Company
Eli Lilly and Company
Category
Research & Development
Job Type
Full Time | Regular
Job ID
R-75917
Position Summary
The Materials Science Crystallization Advisor-SMDD will join the Synthetic Molecule Design and Development (SMDD) organization, focusing on solid-form screening, characterization, and crystallization of small molecules, peptides, oligonucleotides, and intermediates. The role involves providing technical leadership in the crystallization of new therapeutic modalities and ensuring successful scale-up processes for drug manufacturing.
Key Responsibilities
Solid-Form Screening and Crystallization:
Conduct solid-form screening and characterization of small molecules, peptides, oligonucleotides, and intermediates.
Scale-up crystallization for small molecules and peptide fragments.
Troubleshoot complex technical issues related to solid form assessment and particle properties.
Workflow and Data Integration:
Develop workflows for solid-state integration with automated data analysis.
Maintain laboratory area and instrumentation related to solid-state and crystallization processes.
Communication and Documentation:
Document scientific results and provide clear communication through written and verbal presentations.
Technical Leadership:
Serve as a consultant for project teams solving complex solid-state related problems.
Education and Experience
Ph.D. degree in Physical Science (e.g., Chemistry), Pharmaceutics, or a related discipline.
Additional Skills/Preferences
Familiarity with solid-state analytical tools (e.g., XRPD, DSC, TGA, DVS, HPLC) and crystallization instrumentation (e.g., Easymax, Crystal 16).
Demonstrated experience in solid form screening, crystallization, salt, and cocrystal screening for pharmaceutical solids.
Experience in scale-up crystallization of small molecules or peptides.
Strong understanding of the impact of pharmaceutical solid-state science on drug product performance and manufacturing.
Compensation
Anticipated Salary Range: $121,500 – $198,000 annually.
Eligible for company bonus program (based on company and individual performance).
Benefits
401(k) plan and pension
Vacation and paid time off
Medical, dental, vision, and prescription drug benefits
Flexible spending accounts (healthcare, dependent care)
Life insurance and death benefits
Wellness programs (EAP, fitness benefits, clubs, and activities)
Other leave of absence benefits
Travel
0-10% travel required.
On-Site Position
Located at Lilly Technology Center-North (LTC-N), Indianapolis, IN.
Equal Opportunity Employer
Lilly is an equal opportunity employer dedicated to diversity and inclusion.
Employee Resource Groups (ERGs)
Includes groups such as Black Employees at Lilly, Organization of Latinx at Lilly (OLA), Lilly India Network, PRIDE (LGBTQ+ Allies), Women’s Initiative for Leading at Lilly (WILL), and others.
Accommodation
Applicants needing accommodations during the application process can request assistance via the Accommodation Request Form.
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