Scientist II – Protein Biology (Antibody Development)
Location: Bangalore, Karnataka, India
Job ID: R-01339278
Employment Type: Full-Time
Work Mode: Fully Onsite
Function: Research & Development
Work Schedule: Monday to Friday
Work Environment: Laboratory (PPE Required)
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is a global leader in serving science, enabling customers to make the world healthier, cleaner, and safer. With an annual investment of approximately USD 1.4 billion in research and development, Thermo Fisher Scientific provides its teams with advanced technologies, collaborative environments, and global platforms to drive scientific innovation.
Through its industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Patheon, PPD, and Unity Lab Services, the organization supports life sciences research, analytical testing, diagnostics, and biopharmaceutical manufacturing worldwide.
About the Antibody Development Team
The Antibody Development team is at the forefront of protein and antibody engineering, focusing on the design, development, validation, and optimization of high-quality antibodies. The team applies advanced molecular biology, protein biology, and biophysical characterization techniques to deliver robust, research-grade and application-ready products.
Role Overview
The Scientist II – Protein Biology will play a key role in advancing antibody and protein engineering programs. This position requires a high degree of scientific independence, technical depth, and the ability to translate research concepts into validated products. The Scientist II will lead experimental workflows, contribute to product development strategies, and collaborate across multidisciplinary teams to ensure high-quality scientific outcomes.
Key Responsibilities
Independently plan, design, and execute protein biology and antibody development experiments
Lead antibody engineering workflows from concept through validation and product readiness
Apply advanced protein characterization techniques to evaluate antibody performance, affinity, and specificity
Support and mentor junior scientists and contribute to knowledge sharing within the team
Analyze, interpret, and present experimental data through technical reports and scientific presentations
Collaborate with cross-functional teams to optimize workflows, improve product quality, and drive continuous improvement
Provide technical troubleshooting and scientific guidance to resolve complex experimental challenges
Ensure strict adherence to GLP, laboratory safety standards, and quality systems
Required Qualifications and Experience
Master’s degree in Life Sciences with a minimum of 5 years of relevant industry or research experience,
OR
PhD in Life Sciences with at least 2 years of postdoctoral or industry experience
Educational background in Molecular Biology, Immunology, Biotechnology, Biochemistry, Structural Biology, Protein Design, or Protein Engineering
Required Technical Expertise
Extensive hands-on experience with antibody development platforms including hybridoma, single B-cell, and recombinant antibody technologies
Strong knowledge of molecular biology, cell biology, protein engineering, immunoassays, and protein conjugation
Experience with biophysical characterization techniques such as Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI)
Expertise in antibody characterization including affinity measurements, epitope binning, and structure-function analysis
Proven experience in protein expression systems, protein purification, and protein–protein interaction studies
Proficiency in high-throughput molecular biology workflows including cloning, plasmid construction, PCR, restriction digestion, ligation, transformation, and sequencing
Strong experience with biochemical and immunoassay techniques such as ELISA, SDS-PAGE, Western blotting, immunofluorescence (IF), and immunohistochemistry (IHC)
Preferred Skills and Additional Qualifications
Experience in antibody or protein conjugation chemistry
Demonstrated ability to troubleshoot complex scientific problems independently
Proficiency in molecular biology and sequence analysis software, MS Office applications, and statistical tools such as GraphPad Prism
Authorship or co-authorship of peer-reviewed scientific publications
Strong understanding of standard and emerging research protocols
GLP experience is mandatory
Work Environment and Safety
Laboratory-based role requiring the use of personal protective equipment, including lab coats, gloves, safety glasses, and other required PPE
Compliance with all laboratory safety, quality, and regulatory standards
Compensation, Benefits, and Equal Opportunity
Thermo Fisher Scientific offers competitive compensation, performance-based incentives, comprehensive healthcare coverage, and a broad range of employee benefits. Employees benefit from long-term career growth, exposure to global research programs, and a culture rooted in integrity, intensity, involvement, and innovation.
Thermo Fisher Scientific is an Equal Opportunity Employer and values diversity and inclusion. All qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, or any other legally protected status.
Apply now to contribute to advanced protein and antibody engineering at a global leader in life sciences research.
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