Senior Principal Investigator | Process Chemistry & API Development | Bengaluru, India
Company: Syngene International Limited
Location: Bengaluru, Karnataka, India
Division: Dedicated Centre – Chemical Development & API Supply (BBRC)
Experience Required: 12–18 years
Job Type: Full-Time, On-Site
About Syngene
Syngene International Ltd., established in 1993, is a global, innovation-driven discovery, development, and manufacturing organization. We provide integrated scientific services across pharmaceuticals, biotechnology, nutrition, animal health, consumer goods, and specialty chemicals.
Our clients include global leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. Syngene’s innovative culture is fueled by a team of 4,240+ scientists, dedicated to solving complex scientific challenges, accelerating R&D productivity, reducing time-to-market, and lowering innovation costs.
Role Overview
We are seeking a Senior Principal Investigator (6-II) to provide strategic and scientific leadership within our process chemistry and API development function. This role will lead process development teams, oversee scale-up technologies, and ensure efficient execution of research strategies while maintaining the highest quality and regulatory standards.
The ideal candidate will combine deep technical expertise in organic chemistry with strong leadership and project management skills to mentor teams, optimize resources, and drive innovative solutions in API and chemical development projects.
Key Responsibilities
Leadership & Team Management:
Lead and mentor a team of process development scientists to achieve project objectives efficiently.
Provide visionary guidance to multiple project groups in process chemistry research and scale-up operations.
Allocate resources based on project priorities and manage cross-functional teams in a matrix organization.
Conduct performance appraisals, set objectives, and foster professional development for team members.
Scientific & Technical Execution:
Lead process chemistry efforts for New Chemical Entities (NCEs), including process research, development, and scale-up technologies.
Apply expertise in modern and classical organic chemistry to anticipate challenges and provide proactive solutions.
Support the Head of Process R&D in implementing strategic research initiatives.
Optimize processes to enhance team productivity and overall operational efficiency.
Communication & Stakeholder Engagement:
Present project updates, technical results, and key challenges to management and stakeholders with clarity and professionalism.
Provide technical know-how and expert advice on complex chemistry problems.
Qualifications & Experience
Education: Ph.D. or Post-Doctoral experience in Organic Chemistry.
Experience: 12–18 years in process chemistry, API development, and preclinical/clinical candidate molecule development, including leadership of large scientific teams.
Demonstrated expertise in process development, scale-up technologies, and matrix management.
Technical & Functional Skills
Advanced knowledge of process chemistry and API development for clinical and preclinical molecules.
Expertise in project management, team leadership, and cross-functional collaboration.
Proven track record in process optimization, problem-solving, and innovation in organic chemistry.
Behavioral & Leadership Skills
Strategic and analytical thinker with the ability to influence and inspire teams.
Excellent verbal and written communication skills.
Strong emotional intelligence, adaptability, and the ability to manage matrixed teams and sub-functions effectively.
Motivates and energizes teams to achieve high performance in a dynamic research environment.
Equal Opportunity Employer
Syngene is committed to equal employment opportunity (EEO) for all candidates, regardless of age, color, national origin, citizenship, disability, race, religion, gender, sexual orientation, or any legally protected characteristic. Reasonable accommodations will be provided for qualified individuals with disabilities.
Apply Now to lead cutting-edge process chemistry and API development projects at Syngene and drive innovation in global pharmaceutical research.
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