Human Genetics Lead - Diabetes, Obesity, And Complications

Eli Lily

4+ years

$153,750-$270,600

Remote

10 Jan. 30, 2025

Job Description

Job Type: Full Time Education: B.Sc, M.Sc, B.Pharm, M.Pharm, LifeScience Graduates Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Title: Human Genetics Lead - Diabetes, Obesity, and Complications
Category: Research & Development
Job Type: Full-Time, Regular
Job ID: R-66446

Company Overview:

Eli Lilly and Company is a global healthcare leader, headquartered in Indianapolis, Indiana. We are committed to improving lives worldwide by discovering and delivering life-changing medicines. Our employees work across the globe to make a meaningful impact on patients' lives, contribute to the understanding and management of diseases, and engage in community-based volunteerism and philanthropy. At Lilly, we are dedicated to creating an environment where everyone feels valued and can contribute to groundbreaking advancements in healthcare.

Position Overview:

The Human Genetics Lead - Diabetes, Obesity, and Complications will play a pivotal role within Lilly’s Diabetes, Obesity, and Complications Therapeutic Area (DOCTA). This leadership role is designed for an individual with deep expertise in human genetics and metabolic disease biology. You will lead a team of geneticists, develop and execute strategic initiatives, and foster collaborations with internal and external partners. This position will enable you to influence disease target identification, expand indications, and enhance the understanding of disease mechanisms to advance therapeutic discovery. You will have the opportunity to impact one of the most exciting areas of medical research today.

Key Responsibilities:

Scientific Leadership & Strategy: Provide visionary leadership in human genetics to position Lilly at the forefront of genetics research for diabetes, obesity, and complications.
Team Leadership: Build, lead, and mentor a diverse team of experts in statistical/population genetics, genomics, and genetic epidemiology.
Resource Management: Manage internal hires, postdoctoral fellows, contractors, vendors, and strategic partners to execute on strategic priorities.
Innovative Execution Models: Design and implement a visiting scholar program for senior human genetics researchers.
Data Integration: Optimize the use of large-scale public genetic and genomic resources. Integrate population biobanks and genome sequencing with patient-derived data from clinical trials to generate novel insights.
Target Identification & Validation: Align with DOCTA’s strategic priorities to identify and validate novel therapeutic targets, biomarkers, and clinical trial designs.
Cross-Functional Collaboration: Lead initiatives to translate genetic/genomic findings into actionable insights that inform drug discovery and clinical trial strategies.
Strategic Collaborations: Drive strategic collaborations with external partners to access unique genetic datasets and amplify research capabilities.
Scientific Representation: Represent Lilly at key scientific conferences, stay engaged with the broader genetics and genomics community, and ensure Lilly is at the forefront of innovation.
Communication & Publications: Interpret and communicate the results of genetic analyses through scientific manuscripts, posters, and presentations. Effectively share the group's progress with internal and external stakeholders.
Standard Methodology Implementation: Ensure the implementation of best practices in scientific project execution and documentation (e.g., JIRA, Confluence, Git, code reviews).
Genetic Analysis Execution: Perform hands-on genetic analyses when necessary and develop reproducible pipelines for genetics analyses within the team.

Minimum Qualifications:

Education: PhD or equivalent in Human Genetics, Statistical Genetics, or a related field.
Experience: At least 4 years of industry experience, including 3+ years in a leadership role.

Additional Skills & Preferences:

Team Building & Leadership: Demonstrated success in building, mentoring, and managing scientific teams (3+ years managing direct reports).
Human Genetics Workflows: Extensive experience with human genetics workflows, including WGS, WES, and genotyping data analysis for association studies, polygenic risk scores, and rare variant analysis.
Clinical & Biomedical Informatics Data: Experience working with clinical and observational biomedical data sets, including clinical trials, EHRs, and large biobanks (e.g., UK Biobank).
Pharma/Biotech/Academia Experience: Proven track record in high-impact research programs in pharma, biotech, or academia. Knowledge of drug development is strongly preferred.
Clinical/Diagnostic Genetics: Experience in clinical/diagnostic genetics, including ACMG guidelines for variant annotation, is preferred.
Publications: Strong record of publications in top-tier scientific journals.
Collaboration Skills: Excellent interpersonal and communication skills to engage cross-functional teams and external partners.
Project Management: Ability to manage multiple competing priorities and work efficiently in a fast-paced environment.
Matrixed Organization Leadership: Proven success in leading within a matrixed organization and driving outcomes through collaborative teamwork.

Why Join Lilly?

At Lilly, you will have the opportunity to contribute to life-changing research in the treatment of diabetes, obesity, and related cardiometabolic diseases. Join a team that thrives on scientific collaboration and innovation, working to deliver impactful medicines to patients. As a member of Lilly, you’ll be part of a company that is committed to professional development, continuous learning, and fostering a culture of inclusion and scientific excellence.

Lilly is an Equal Opportunity Employer (EEO). We are committed to ensuring that all individuals have an equal opportunity to compete for jobs and that people with disabilities can actively engage in the workforce. If you need accommodations during the application process, please contact Lilly Human Resources at Lilly_Recruiting_Compliance@lists.lilly.com.

Compensation:

The anticipated annual compensation for this position ranges from $153,750 to $270,600 depending on education, experience, skills, and geographic location.

#WeAreLilly

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Human Genetics Lead - Diabetes, Obesity, And Complications

Job Description

Company Overview:

Position Overview:

Key Responsibilities:

Minimum Qualifications:

Additional Skills & Preferences:

Why Join Lilly?

Compensation:

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