Clinical Trial Manager – Aligos Therapeutics | South San Francisco, CA
Job Summary
Aligos Therapeutics, a leading clinical-stage biopharmaceutical company, is hiring a Clinical Trial Manager to support multiple early-phase clinical programs for chronic hepatitis B, MASH, and COVID-19. Based in South San Francisco, this full-time position offers a competitive salary range of $136,000 to $159,000, plus bonus, equity, and comprehensive benefits. The role involves full-spectrum clinical trial oversight, vendor management, and regulatory compliance across a dynamic portfolio of investigational drugs.
Key Responsibilities
Develop and execute detailed clinical trial plans in line with industry standards.
Manage timelines, study budgets, and cross-functional coordination.
Oversee CROs, central labs, and other vendors throughout study lifecycle.
Draft, review, and coordinate regulatory documents (protocols, ICFs, CRFs, IBs).
Set up and maintain (e)TMF, ensuring GCP compliance and inspection readiness.
Lead data review and contribute to final clinical study reports.
Support drug supply logistics in collaboration with CMC teams.
Identify risks and implement mitigation strategies across studies.
Mentor junior staff and contribute to SOP/process improvement initiatives.
Required Skills & Qualifications
Bachelor’s degree in a scientific field or RN degree (required).
Minimum 5 years of experience in clinical operations/monitoring in pharma, biotech, or CRO.
Hands-on experience with early-stage clinical trials, especially in NASH, antivirals, or infectious diseases.
Strong knowledge of ICH-GCP, FDA, and EMEA regulations.
Experience in vendor management and cross-functional coordination.
Excellent communication, documentation, and decision-making skills.
Proficiency in clinical systems and documentation practices.
Perks & Benefits
Competitive Salary: $136,000 – $159,000 annually
Annual Bonus + Equity Options
Medical, Dental, Vision Insurance
Life and Disability Insurance
Flexible Spending Accounts (FSA) & Health Savings Account (HSA)
Paid Time Off (PTO) and Holidays
401(k) Retirement Plan
Employee Stock Purchase Plan (ESPP)
Career growth in a collaborative and innovative biotech environment
Company Description
Aligos Therapeutics is a science-first biotech company focused on developing transformative therapeutics for liver and viral diseases, including chronic hepatitis B, MASH, and COVID-19. With three compounds in the clinic and a growing pipeline, Aligos offers an agile, fast-paced environment with industry-leading scientific talent.
Work Mode
On-site – South San Francisco, CA
(Approximately 10–15% domestic travel may be required.)
Call to Action
Are you ready to lead clinical trials that shape the future of liver and infectious disease treatments? Join Aligos Therapeutics and make a meaningful impact. Apply today to accelerate your clinical operations career in biotech.
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