LCMS Method Development Scientist III – Bioanalytical Research
Category: Clinical / Bioanalytical
Location: Indianapolis, Indiana, United States
Job Type: Full-Time
Job ID: 2542434
About Labcorp
Labcorp is a global leader in life sciences and contract research, providing comprehensive laboratory testing and drug development services to the pharmaceutical and biotechnology industries. With a track record of supporting the development of one-third of all prescription medicines, Labcorp empowers scientists and healthcare innovators to accelerate the delivery of life-changing therapies.
Role Overview
Labcorp is seeking an experienced LCMS Method Development Scientist III to join the bioanalytical team in Indianapolis, IN. In this role, you will lead method development for a diverse portfolio of molecules across multiple species and matrices. You will act as the scientific lead in troubleshooting, method optimization, and technical support, serving as a subject matter expert for both internal teams and clients.
This position offers opportunities to publish research, present scientific findings, and contribute to cutting-edge bioanalytical development projects.
Key Responsibilities
Develop and validate highly sensitive, reliable LC/MS/MS assays for pharmaceuticals in biological fluids and tissues.
Conduct complex analytical methods, applying scientific problem-solving to novel and challenging scenarios.
Lead scientific approaches in bioanalytical and mass spectrometry studies, interpreting experimental data in line with regulatory requirements.
Act as a technical advisor within cross-functional project teams.
Respond efficiently to unscheduled deadlines, client requests, and urgent project needs without compromising quality.
Produce method development reports, analytical documentation, and scientific publications.
Participate in client visits and technical discussions, representing Labcorp’s expertise.
Contribute to long-term planning and departmental technical policies.
Support method development for specialized molecules such as oligonucleotides, ADCs, or biologics.
Required Education & Experience
PhD in Analytical Chemistry or equivalent degree with approximately 2 years of relevant experience (or equivalent professional experience).
Proven expertise in LC/MS/MS, HPLC, and other analytical instrumentation.
Demonstrated experience in analytical method development, validation, and bioanalytical research.
Skilled in data compilation, interpretation, reporting, and regulatory-compliant documentation.
Experience in scientific presentations and publication preparation.
Familiarity with laboratory automation software, system software, and Microsoft applications.
Prior experience with oligonucleotides, ADCs, or similar method development is highly desirable.
Compensation & Benefits
Pay Range: $62,000 – $155,000 per annum (based on experience, skills, and internal equity).
Eligible employees working 20+ hours per week receive comprehensive benefits, including:
Medical, Dental, Vision, Life, STD/LTD coverage
401(k) Retirement Plan
Paid Time Off (PTO) or Flexible Time Off (FTO)
Tuition Reimbursement
Employee Stock Purchase Plan
Special Considerations
Overtime and weekend work as required.
Mandatory immunization and screening as per Labcorp policies.
Participation in technical conferences and exhibitions.
Work may involve handling potentially hazardous substances.
Why Join Labcorp?
Work with a world-leading contract research organization in a collaborative, innovative environment.
Contribute to cutting-edge bioanalytical research that accelerates the development of life-saving therapies.
Gain experience in method development, regulatory compliance, and advanced analytical techniques.
Opportunities for career advancement, publications, and international scientific collaborations.
Equal Opportunity Employer
Labcorp is committed to fostering a diverse and inclusive workforce. We consider all qualified applicants without regard to race, religion, color, national origin, sex, disability, veteran status, or other legally protected characteristics.
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